Participating Databases

United States Environmental Protection Agency Integrated Risk Information System Go to external website



Type of information that can be found via eChemPortal:

The IRIS database has the following types of information on the web site: toxicological assessments, RfD and RfC tables, schedule of updates/new additions (listed in IRISTrack), advanced searching and a compare chemicals feature.

General information:

The Integrated Risk Information System (IRIS) is a human health assessment program that evaluates quantitative and qualitative risk information on effects that may result from exposure to environmental contaminants. IRIS was initially developed for EPA staff in response to a growing demand for consistent information on substances for use in risk assessments, decision-making, and regulatory activities. The information in IRIS is intended for those without extensive training in toxicology, but with some knowledge of health sciences.  Please see:  http://epa.gov/iris/intro.htm Go to external website

Hazard information

IRIS contains the following types of hazard information: CAS number, substance name, keyword, critical effect, tumor type, toxicity value, human carcinogenicity, and uncertainty factor.

Search capabilities:

IRIS search capabilities include:  CAS number, substance name, keyword, critical effect, tumor type, toxicity value, human carcinogenicity, and uncertainty factor.

Maintenance:

The IRIS program maintains the integrity of the chemical assessments by following the 2009 IRIS process prior to posting updated or new assessments to the IRIS Web site and database. These are announced on the IRIS Agenda and then can be tracked as they follow the IRIS Process for development through IRISTrack. The final assessments are then posted throughout the year. The IRIS Program is managed by EPA’s National Center for Environmental Assessment (NCEA).

Peer review:

All IRIS Assessments follow a rigorous peer review process that is documented on the following web page:
http://www.epa.gov/iris/process.htm Go to external website



Top of Page